San Francisco head coach Kyle Shanahan said that Samuel strained his right hamstring "pretty good" during Sunday's 32-29 win over Seattle and is "going to miss at least a couple weeks," David Lombardi of SFStandard.com reports.

San Francisco head coach Kyle Shanahan said Monday that Wallow will miss "at least a couple of weeks" due to a hamstring strain, Nick Wagoner of ESPN.com reports.

doubtful

questionable

Thompson (ankle) could return in Week 6 against Washington, Matt Barrows of The Athletic reports.

questionable

Head coach Kyle Shanahan said Monday that Kirk (calf) is "unlikely" to return to practice this week, Nick Wagoner of ESPN.com reports.

Head coach Kyle Shanahan said Monday that Martin's (hamstring) status will be evaluated "in these next couple of days," Nick Wagoner of ESPN.com reports.

Greenlaw's appeal of a one-game suspension was denied by the NFL on Tuesday, Adam Schefter of ESPN reports.